Sentence examples for intermediate stabilized from inspiring English sources

The electron-rich Ni(I) intermediate, stabilized by a redox-active α-diimine ligand, is responsible for the chemoselectivity toward reductive cyclization as opposed to the redox-neutral cycloisomerization observed with previous Ni II) catalysts.

The protonation consequently cleaves the adenine in the zwitterionic form from the ribose by breaking the bond between N9 of the adenine and C1 of the ribose, thus leading to the formation of a cationic ribose intermediate stabilized by Glu177 at the transition state.

Furthermore, LF constructs with the N-end rule stabilizing residues Met or Gly, and the intermediate stabilizing residues, His and Ala, resulted in a similarly low TTD (Table 2).

Documenting a significant quadratic term is not sufficient to conclude that a fitness peak occurs at the extremes (disruptive selection) or at intermediate (stabilizing selection) trait values [ 36].

Figure 2B represents a more complex model with two sequential binding intermediates, where the formation of a second intermediate stabilizes the open state of the partner, thereby providing means for an easy access to the originally hidden binding site.

When the enzyme is in the presence of 50 μM CPT the cleavage/religation equilibrium is shifted towards cleavage, since CPT reversibly binds to the covalent DNA enzyme intermediate, stabilizing it and slowing down the religation rate, as indicated by the band indicated by the asterisk corresponding to the substrate cleaved at the preferred site [ 5, 29, 30].

Deposition rates decreased with increasing rotation speed, indicating that Cu(I) intermediates, stabilized by NH3, diffuse away from the Cu surface before they reduce to Cu(0).

Together, the data suggests that the 12 18 mers are trapped as 'off-pathway' intermediates, stabilized by NEFAs.

Taken together, the data discussed above demonstrate that intermediates, stabilized by both native and non-native interactions, are commonly formed en route to the native state.

The results suggest that the folding energy landscapes of even the smallest proteins possess significant ruggedness in which intermediates stabilized by both native and non-native interactions are common features.

(2) Good yields for the elimination reaction product methylglyoxal are obtained from the LDM-catalyzed reaction of GAP, because of the loss of interactions between the tip residues of loop 6 and the enediolate intermediate, which stabilize the intermediate toward elimination of inorganic phosphate.