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In addition to a pre and post measurement, an intermediate measurement will be conducted.
There is a measurement at baseline, an intermediate measurement (6 months after baseline), after the intervention period (12 months after baseline), and a follow-up measurement (6 months after end of intervention, 18 months after baseline).
19) Observation time a) In chronic diseases long-term observations (at least 1 year) with intermediate measurement time points are highly recommended, in order to evaluate cost-effectiveness as developed over time.
Mixed-model repeated measures (MMRM) analyses will be used since this approach can include participants with missing data and incorporate data from intermediate measurement time points of four and eight weeks.
All three intervention groups (i.e., the tailored letters, the motivational calls, and the combined version) were equally and significantly more effective than the control group in increasing physical activity (hours/day), intake of fruit (servings/day), and consumption of vegetables (grams/day) from baseline to the intermediate measurement (week 25), follow-up 1 (week 47) and 2 (week 73).
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Viral load is measured at cohort visits scheduled every six months but intermediate measurements are also made so that most patients are measured on average once every three months.
The core metrics for population health impact and outcomes all have population denominators, and will be measured at baseline and endline with additional intermediate measurements of coverage, nutritional status, and fertility where possible.
For the intermediate measurements, the variation of CFS probabilities is more important for both response variables.
We only find some significant districting parameters and intermediate measurements that may lead to better plans.
These intermediate measurements of districting plans can be used to select top proportion of plans for further simulation evaluation.
The weights for two intermediate measurements became [0.4, 0.6] tentatively for compactness and standard deviation of CFS probabilities among districts.
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