Sentence examples for intermediate initiation from inspiring English sources

Therefore, the "intermediate" initiation context of p42 and LAP appeared to be sufficiently strong to support initiation of most of the scanning ribosomes in the absence, but not in the presence, of uORF translation.

Patients were categorized into three groups according to their timing of initiation of Tx2: early initiation group (≤18 months since diagnosis), intermediate initiation group (19 36 months), and late initiation group (>36 months).

HSBs initiated and terminated several of these tasks earlier than LSBs, and wild-type bees generally demonstrated intermediate initiation and termination ages (log-rank test, Nmin = 11, Nmax = 113, Nmedian = 56.5, Fig.  3).

For mRNA-type promoters, transcription factor D (TFIID) first binds to the TATA box via its TBP subunit, forming an intermediate pre-initiation complex (PIC) that can further be stabilized and correctly oriented by TFIIB [3],[4].

The open promoter complex (OC) is a central intermediate during transcription initiation that contains a DNA bubble.

We previously demonstrated that, in the budding yeast Saccharomyces cerevisiae, eIF3 closely cooperates with several other eIFs to stimulate recruitment of methionyl‐tRNAiMet and mRNA to the 40S ribosome and that it forms, together with eIFs 1, 2, and 5, an important intermediate in translation initiation called the multifactor complex (MFC).

Thus, the py48S here is an important intermediate in the initiation pathway following AUG recognition by tRNAi but prior to eIF1 dissociation.

In summary, these N-nitrosamines are genotoxic and might be alternatives to their hydroxylamine analogues as activated intermediates leading to initiation of colon cancer in individuals with colitis.

However, if real, reduced AKT Ser473 phosphorylation would appear to have had no significant impact on the two downstream translation initiation intermediates p70 S6K and 4E-BP1.

Low expression levels of Twinkle K319E lead to the appearance of a sharp double-stranded bubble-arc in a fragment containing the non-coding region of mtDNA, while the club-headed double bubble-arc typical for RNA-rich initiation intermediates was reduced.

Rad54 and Rdh54 displace Rad51 from dsDNA and this could be important to remove unproductive association of Rad51 with dsDNA during presynapsis, thus increasing the pool of Rad51 available for HR, for turnover of Rad51 upon completion of recombination, or to uncover the 3′ end of paired intermediates to allow initiation of DNA synthesis (Solinger et al. 2002; Holzen et al. 2006; Shah et al. 2010).