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Supplementation with an NAD intermediate increases NAD+ levels in peripheral tissues such as liver and skeletal muscle, but not in brain [ 50].
In particular, it was found that enhanced T-cell development was only obtained with intermediate increases in Wnt signal activation, with early thymocyte subsets (DN) showing the greatest requirement for Wnt signaling.
In contrast, maintenance of a multipotent HSC state was associated with mild increases in Wnt signal activation, while myeloid differentiation was only promoted by mild to intermediate increases in activation, and high to very high increases in Wnt activation were detrimental to murine HSC self-renewal and differentiation (Luis et al., 2011).
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Descriptively, Rhyme yielded the least consistent and Rhyme&Melody the most consistent increase in learning outcome over Prose, with Melody yielding an intermediate increase.
ICRP 62 [20] recommended that the maximum radiation dose that causes a 'minor to intermediate' increase of risk levels while preserving social benefit levels that are 'intermediate to moderate' has an effective limit of 10 mSv/year [20, 21].
An intermediate increase (1.4-fold) in locomotor activity was observed in VAChTFloxNeo/FloxNeo mice when compared to wild-type controls (Fig. 8A and B).
ANS, by binding to the newly exposed hydrophobic sites, displaced the equilibrium between the native form of plasminogen and the expanded intermediate; the faster the expanded intermediate increased in concentration, the faster precipitation occurred.
When both cPDS and BG4 are present, an intermediate increase in the folding rate was observed.
In this case, there was no intermediate increase in body weight.
The transformation of parC alone conferred an intermediate increase in the MICs (ciprofloxacin 2 mg/L, levofloxacin 4 mg/L).
The pericarp and the septa showed the highest climacteric rise in ethylene production rate, while the placenta and the columella showed an intermediate increase.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com