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Highest uptake (whole organ) occurred in lungs (22% Dose; weight ∼1246 g), liver (23%; weight ∼1677 g) and intermediate in brain (10%; weight ∼1600 g).
A. HsamiR-128 has high expression levels in brain primary tumors, low in other primary tumors and intermediate in brain metastasis samples (see Table 2).
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Later studies showed the presence of saturated side chain intermediates in brain, skin, and eventually in all tissues examined (Schroepfer, 1982).
Although a wide variety of intermediate events in brain development connect the initial effects of organophosphates on neural cell differentiation to the eventual synaptic and behavioral defects (Pope 1999; Slotkin 2004, 2005), little information is currently available about specific cellular mechanisms that render the developing brain so vulnerable to these agents.
Although other studies have suggested that changes in the intermediate filament proteins in brain tumors are associated with tumor malignancy and invasiveness, the role of nestin molecules in the nucleus of tumor cells still remains unclear.
Both mPR130 transcripts have a similar expression pattern, being high in kidney and heart, intermediate in skeletal muscle, brain, liver and testis and low in lung and spleen.
At birth, neonatal Hg concentrations were highest in kidney, intermediate in liver, and lowest in brain.
Andreasen et al. (2012) used a machine learning algorithm to identify genes/SNPs that were interacting with one another and predicting a continuous outcome measure that is a biologically meaningful phenotype ("intermediate phenotype") for schizophrenia: changes in brain structure occurring after the onset of the illness.
In Gfap- luc transgenics that are wild-type at the Gfap locus (Gfap +/+), luciferase activity was highest in the spinal cord, intermediate in olfactory bulb, hippocampus and brain stem, and lowest in cerebral cortex and cerebellum.
The homosexual transsexual sample was intermediate in volume on all six brain structures, significantly different from the male controls on five of the six (and significantly different from the female controls on all six).
Methamphetamine's clearance was fastest in heart and lungs (7 16 minutes), slowest in brain, liver and stomach (>75 minutes), and intermediate in kidneys, spleen and pancreas (22 50 minutes).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com