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Their formation occurs via a common intermediate in a kinetically significant step.
They hit the jackpot with the first molecule they tried, α-ketoglutarate (α-KG), an intermediate in a metabolic cycle that helps a cell extract energy from food.
To a solution of the intermediate in a solvent mixture of MeOH (5 mL) and H2O (5 mL) was added excessive Et3N.
In order to determine the nature of PVP intermediate in a BPM, one face of the membrane was coated with PVP solution and its contact angle was measured.
By means of acidic depolymerization, glucose can be produced as an intermediate, in a process in which glucose is dehydrated to 5-hydroxymethylfurfural and subsequently generates levulinic acid.
During embryonic development and fracture repair the majority of bone is formed indirectly from a cartilage intermediate in a process called endochondral ossification.
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GTT1 may therefore have arisen via an RNA intermediate in an ancestral Candida species.
The rate-limiting step of assembly involves stabilization of high-energy intermediates in a kinetic step termed nucleation.
Laser-ionization mass spectrometry is employed to record concentration profiles of radical intermediates in a low-pressure premixed laminar flame.
I met Abdul*, one of these intermediates, in a small village on the outskirts of the rainforest.
This approach of modeling the intermediates in a pathway has been widely used in both chemistry and biology.
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