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The M0418 construct demonstrated a reactivity profile in which residues P59, F62, P63 and K65 were most critical for the interaction; I56, G61 and Y66 were of intermediate importance while several others, for example, S57 and E60, were less important.
The physical comfort, emotional support, and continuity and transition dimensions were found to be of intermediate importance for PCC, and the family and friends dimension was clearly the least important.
Importance sampling (IS) settles the inconvenient sampling and difficult propagation through the incorporation of an intermediate importance distribution or sequential distributions.
This technique has allowed the identification of the amino acids of high or intermediate importance in the CD22-mab 8015 complex.
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merus being intermediate in importance.
In this study we analyzed centralities related to local (degree and eigenvector scores), intermediate (topological importance up to 1 and 4 steps) and global (betweenness and closeness) scale.
We computed a number of centralities varying from local scale (degree and eigenvector scores) to intermediate scale (topological importance up to 1 and 3 steps) and finally to global scale (betweenness and closeness).
Based on the responses to the round 1 questionnaire, we categorised the criteria into high (70% or more respondents ranked criteria as 6 or 7 on the scale of importance), intermediate (50-69% ranked criteria as 6 or 7 on the scale of importance) and moderate priorities (less than 50% ranked criteria as 6 or 7 on the scale of importance) for the second round questionnaire.
It is also becoming increasingly clear, that regulation of Jmj activity through levels (normoxic vs hypoxic) of the cosubstrate O2, or indirectly through HIFα-mediated responses, reactive oxygen species or metabolic intermediates is of importance [ 154, 253, 333, 334].
The importance of intermediate filaments in muscle is further strengthened by murine models in which genetically designed intermediate filament mutations are expressed, leading to progressive skeletal or cardioskeletal myopathy in affected mice.
Differences in the importance of intermediate predators and mesograzers (>7 mm) along the salinty gradient have important implications for both trophic transfer and resilience of eelgrass meadows to present and future stressors.
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