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Accordingly, a subclassification into (i) 'ghost' pseudogenes with some intermediate functionality, i.e. similar to a functional gene and transcribed and/or functional, and (ii) 'dead' pseudogenes that lack any functionality has recently been proposed.
Besides completely functional and non-functional alleles, we have found a widespread allelic class with intermediate functionality.
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The inhibition may even act directly on the protein and not on intermediate functionalities along the signalling pathways between the receptors of the stimuli and the protein.
For the aliphatic thiol-specific OR2C1 the 11 alleles have similar intermediate-level functionality prediction.
Using a between-subjects design, we varied the depth-of-processing involved in the word judgment task: participants judged the words based on personal experience (deep/elaborative processing), word length (shallow), or functionality (intermediate).
In practice, this should be enforced while allowing some basic functionality for intermediate delegated nodes such as searching through encrypted content.
In contrast, NLRP3 functionality in intermediate stage melanoma cells requires activation of the IL-1 receptor by IL-1α in order to secrete active IL-1β.
It is clear from the results of the simulations at varying levels of EGF stimulus that in order to accurately predict the response to EGF stimulus, we need to break down our EGFR model and understand the functionality of intermediate signaling components.
A facile and high yield two-step synthesis of xylo-7-deazaguanine 7, a key intermediate for introducing 3′-amino functionality, is carried out under Mitsunobu conditions.
A single transcription factor, Oct4, was shown to generate haematopoietic stem cells from fibroblasts that could be further differentiated into various myeloid cell types, suggesting functionality of all intermediate precursor states and lineage commitment steps (Szabo et al, 2010).
In addition, the skylights were controlled with a dynamic shading system and delivered a maximum reading below 2000 lx during peak times, at an average of 350 lx, with functionality between 46%and56%6% under the intermediate sky condition.
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