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CNV and deleterious mutations of functional CYP2D6 genes are categorized into four phenotypes based on their ability (rate) to metabolize drugs: A poor (PM), intermediate, efficient (EM), or ultrarapid metabolizer (UM) (Zanger et al. 2004).
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Results with and without normalization were very similar and three groups could be defined, being genotype 1b the most efficient, genotypes 2, 3, and 5 showing an intermediate efficiency, and genotype 4 the less efficient RNA-polymerase.
Neither fairness nor efficiency is a primary aim but an intermediate 'fairly efficient and efficiently fair' PES may bridge the gap between PES theory and practice to increase sustainable ES provision and improve livelihoods.
Considering the sequential EMT-MET, the preliminary hypothesis that an optimal mesenchymal may function as intermediate for efficient cell fate conversions might be more reasonable.
The model also predicts an intermediate energy-efficient gait, or "pendular run", not generally observed in the real world.
Indolizine core structures were synthesized strategically as common intermediates for efficient derivatization.
We and others have proposed that ArnB may oligomerize with other enzymes in the pathway to form a multiprotein complex in vivo where the substrates are channeled between active sites for protection of labile intermediates and efficient synthesis of product.
This intermediate type of efficient cause plays a role in Avicenna's emanationist account of creation.
E. coli AU1 is a useful intermediate host for efficient transformation of C. glutamicum.
Chromate conversion coatings are still one of the most efficient intermediate surface treatments for galvanized steel.
In this study, an approach of intermediate model based efficient and integrated visualization of multidisciplinary simulation data for simulation information reuse is proposed to address the above issues.
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