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Third, C3* could have been introduced into Ecuador from East Asia at some intermediate date by a direct route that bypassed North America.
We show the chronogram for the intermediate date (75 MYA), but we also report the ages of critical nodes in Additional file 2. The analysis was run twice independently for 20 million generations.
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We chose normally distributed age priors to place higher probabilities on intermediate dates and lower probabilities on older and younger dates, which was most plausible in our case.
Fish that arrived early to the spawning grounds tended to be more productive than later fish, although in some years, RS was maximized at intermediate dates.
Most likely, this is because admixtures in human populations have taken place over multiple generations, such that our estimated times represent intermediate dates during the process.
The proposed model is an extension of model by Shaik and Floudas (2007, Industrial & Engineering Chemistry Research, 46, 1764) with several new constraints to deal with additional features such as unit and sequence dependent changeovers, multiple intermediate due dates, handling of shelf-life and waste disposal, and penalties on backlogs and late deliveries.
However, it also appeared that in some years, RS was greatest at intermediate arrival dates (Fig. 4).
Despite the consistently negative linear gradients, in some years the individuals with the greatest RS had intermediate arrival dates (Fig. 4).
Studies on the assembly of neuronal intermediate filaments (IFs) date back to the early work of Alzheimer.
Because of the overlap of BNP levels in the lower and intermediate concentration, to date, the diagnostic value of BNP in this concentration range seems to be poor.
Despite the importance of thioester-forming E3s, the mechanisms by which Ub is ligated from an E3 cysteine remain elusive, because at the time of original manuscript submission there were no structures mimicking an E3∼Ub intermediate, and to date there are none representing an E3∼Ub-substrate complex.
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