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The intermediate binding of probes 50 and 52 probably requires breaking of four intramolecular base pairs.
The intermediate binding of probes 114 and 130 to stem P12 is surprising because in each case five intramolecular Watson−Crick pairs are likely broken.
Qualitatively, MCF7/Her2-18 showeds showed the highest level of cell-associated anti-Her2 antibody-conjugated nanoparticles, MDA-MB-231 cells showed intermediate binding of targeted nanoparticles, and CHO cells showed a low level of nanoparticle binding; this is in agreement with the calculated number of Her2 receptors.
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Of the nine residues, seven were involved in intermediate binding to glucose directly, while the other two, Trp412 and His181, indirectly binding to glucose.
Our finding of a significantly higher response rate among heterozygous patients could possibly point towards several mechanisms being involved in RTX action and that, in RA, these are most optimally balanced in individuals with the intermediate binding variant of FcγRIIIA, that is, FCGR3A-158VF.
As there is a bias towards Ft phosphorylation increasing binding, more intermediate binding occurs in regions of high Fj even though less favourable Ds (light purple) is available.
Probes with normalized intensities between one-third and one-ninth of the maximum normalized intensity are considered intermediate binding.
Using the flow cytometric assay we determined a statistical difference in the binding of Mmm to various bovine host tissues; the highest binding was detected with BoLEC, intermediate binding with BoAEC and low binding with IBoSF and BoFLEC.
The binding signals of the Sir complex and Set1 from ChIP-chip experiments [21] displayed the same patterns: intermediate binding affinity increased expression noise, whereas strong bindings were associated with low expression noise (Fig. 2F).
For example, '' represents the peptide consisting of amino acid residues from 0 to 2. We represent a set of intermediate bindings as set Y. Figure 3 Definition of a set of intermediate bindings in SPAD.
The definition of intermediate bindings among base substructures is arbitrary.
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