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In the interesting case where the 10% of the immunized nodes are randomly selected within the group of people frequently visiting a specific popular location (third strategy), an intermediate benefit, of about 19% epidemic size reduction, is obtained.
Work assessment allowance is a intermediate benefit typically given between sick leave and disability pension.
The propensity for cheaters to disperse is highest with intermediate benefit:cost ratios of cooperative acts and with high relatedness.
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The three vignettes represented the base-case (intermediate benefits/harms ratio), high-risk (with low benefit/harms ratio resulting in higher threshold in comparison with the base-case), and low-risk (high benefit/harms ratio resulting in lower threshold in comparison with the base-case).
Several studies show that physical activity can reduce the risk of cardiovascular disease, but the vast majority of these focus on the short- to intermediate-term benefits or refer to very specific populations.
It has been reported that treatment benefits may increase with illness severity, while others have suggested that only patients with intermediate illness severity benefit, meaning that patients with low or high disease severity will survive or die, respectively, regardless of the provided treatment; some therapies may even be harmful in low risk populations [ 23- 25].
The easiest and intermediate trails also benefit from a snowmaking system, common at the majority of downhill areas in the Northeast, but not often found at many cross-country touring centers.
The available data suggest that prostate cancer especially in patients with intermediate risk profile benefit from dose escalation (reviewed in [ 20]).
A prospective trial (Trial Assigning Individualized Options for Treatment TAILORx) with a planned accrual of at least 10,000 patients intends to answer the question of whether intermediate risk patients benefit from chemotherapy [ 57].
Flavin-dependent halogenases employ an oxidative strategy of chlorination (with formation of a Cl+ equivalent) similar to haloperoxidases and require an electron-rich substrate, although the route through a covalent protein intermediate adds the benefit of regioselectivity (Table 1).
In our present study, we aimed to evaluate the relationship of PIK3CA mutations and GSs representing PI3K pathway activation with key biological features of BC and short-term aromatase inhibitor induced suppression of Ki67, a validated intermediate endpoint for benefit from endocrine therapy [ 11, 36].
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