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The key intermediate 1, 2, 3 are synthesized according to our previous work [28].
This Letter describes the synthetic challenges in synthesising key 1,4-cis-substituted cyclohexylamide intermediate 1 for our research programme.
Then intermediate 1 was cyclized with diethyl oxalate lead to the intermediate 2 by a condensation reaction.
The change from intermediate 1 to 2 must suffer a barrier of 52.7 kcal/mol, which is only 10.9 kcal/mol lower than that for Va.
The government expects immigrants to reach "ESOL Entry 3" or "B1 level", also called "Intermediate 1" in Scotland, before they can be granted citizenship.
The O-acetyl protected intermediate (1) was obtained by treatment of 4-acetoxybenzoylchloride with 4- 2-aminoethyl-benzene)sulfonamide (AEBS) as described by Kuhnast et al. [21].
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The mitochondrial sequences can be integrated in the nuclear genome through two candidate mechanisms: direct DNA transfer and a cDNA intermediate [ 1, 46, 47].
The pyrolysis mechanism of important intermediate 1-hexene of carbon matrix precursor cyclohexane was studied theoretically.
The first intermediate 1,3-benzothiazol-2-ylacetonitrile (2) was synthesized via cyclodeamination reaction of o-aminothiophenol (1) with malononitrile.
The diffusivity of Ag adatoms was preliminarily reduced due to an intermediate 1-nm-thick wetting layer of germanium [15].
Compound 4 reacted with di(1H-imidazol-1-yl)methanethione to obtain the key intermediate 1-cyclopropyl-4-isothiocyanatonaphthalene (5).
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