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Due to the small number of recipients in our cohort with low risk serostatus (n = 13), these recipients were analysed together with the recipients at intermediary risk.
41 Changes in the mortality burden of coronary heart disease, stroke and cancer are modelled through the intermediary risk factors of blood pressure, blood cholesterol and obesity.
In this study there was a suggestion of partial mediation by intermediary risk factors, although, importantly, none of these appeared to completely account for the IQ-IMT association.
Cohort studies of the causation of endpoint phenotypes or even intermediary risk factors by epigenetic characteristics are likely to be just as difficult.
D +/R + constituted the intermediary risk group for both types of transplantations, and the low risk group D −/R + for SOT and D +/R − for HSCT.
The higher risk of TB among the poor can most likely be explained by greater exposure to some, or many, intermediary risk factors such as HIV, under-nutrition, crowded living and working conditions, smoking, harmful use of alcohol, diabetes and indoor air pollution [ 7, 25].
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The identification of intermediary-risk surgical patients likely to require ICU care is difficult.
But the vast majority of that is us performing our role as a financial intermediary and taking risk to help clients make investments or execute transactions.
To demonstrate the ease of use, the robustness and applicability of ADMIRE, we downloaded 689 HumAssayhylation450 Asamplesmples from a study analyzing DNA methylation as an intermediary of genetic risk in rheumatoid arthritis (GEO GSE42861) [ 15].
The process also has numerous intermediaries, a high risk of illegal transactions, high costs, and low efficiency.
That means most investors rely on private banks, brokers or other financial pros as intermediaries, raising the risk they will be steered into products that generate tons of fees for the advisors and not much for the investor.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com