Exact(3)
Mathematical modelling predicts that this type of synthetic gene circuit exhibits bimodal expression; the regulated gene can only be in a "on" or "off" state, without intermediary expression levels, and this was indeed verified experimentally[17].
Consistent with previous studies conducted with different cancer types [ 6, 7, 14, 35, 36], CD11c+ TIDC isolated from 4T1- or LLC-tumor bearing mice exhibit an altered phenotype characterized by intermediary expression of costimulatory (CD80, CD86, and CD40) and MHC II molecules, produce low amounts of the proinflammatory cytokine IL-12, and are poor inducers of T lymphocyte proliferation.
We here present results indicating that, in the mouse lung LLC and mammary 4T1 cancer models, CD11c+ DC infiltrating tumors exhibit a semimature phenotype (intermediary expression of MHC-II, CD80, CD86, and CD83) and significantly suppress T lymphocyte activation in vitro by a mechanism involving CD39 ectoenzyme.
Similar(57)
Though intermediary expressions occupy gigabytes of the computer memory, the obtained coefficients of the normal form are compact enough for presentation in typographic format.
In these samples there were 23 up-regulated, 25 down-regulated and 165 patients with intermediary HIPK2 expression.
These results provide an extended knowledge about the role of intermediary filament expression patterns in SCC's.
In contrast to DNA, where the predominant role is the storage of genetic information, the biological role of RNA varies; ranging from a template-based intermediary in gene expression to playing a direct role in catalysis.
Two transgenic events, P49 and P07, which presented intermediary and high AtUCP1 expression, respectively, were chosen for this study.
Comparative analysis revealed that mammosphere cells had an expression profile intermediary to basal and luminal cell populations indicating that some luminal lineage gene expression had been initiated during culture.
It was therefore the aim of this study to evaluate the expression of intermediary filaments in SCC's in relation to clinico-pathological features, especially for prognostic purposes by the use of tissue micro arrays and immunohistochemistry. Patients with histologically proven squamous cell carcinoma of the oral floor treated surgically were eligible for the study.
In late differentiated preadipocytes, the adenylyl cyclase subtype mRNA expression pattern was intermediary between the undifferentiated and the full differentiation states except for type IV which remained weakly expressed.
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