Last week Mr. Kay gave an interim report indicating that in four months of searching in Iraq he has found none of the W.M.D. that President Bush cited as his principal reason for going to war.
This will require informing patients of the interim results, indicating that further follow-up is necessary to obtain definitive results, and seeking re-consent to continue in this trial.
However, it can be pointed out that an accepted reason for stopping a trial is its 'futility', suggested by interim analyses indicating that it is highly unlikely that the study will show any benefit from the experimental treatment (in our case DEB-TACE) as compared with the control treatment (cTACE) if the trial is continued (Casazza and Casella, 2012).
The fact that the positive effect on the formal examination score was not different using either one or two interim assessments indicates that a second interim assessment taken within a short time interval (i.e. less than 2 h) following the first interim assessment has no added value on the learning effect.
WEST ORANGE, N.J., May 4 — Lou Lamoriello, the Devils' chief executive, president, general manager and interim coach, indicated Friday that he planned to hire another coach after the end of the season, which may come as early as Saturday.
Officials with the interim government indicated that they would pursue an investigation, although senior military leaders in Misurata, where the bodies were taken, said they saw no need for one.
"Our interim report indicates that taking annual FIT testing in high risks groups is invaluable because it reduces the delays in the diagnosis and treatments of cancer," says Dr. Graeme Young, author of an interim study on the value of FIT's as presented at a medical conference in San Diego, California.
The interim analysis indicated that no sample size adjustment was required (see online supplementary appendix 2).
Interim results indicate an increase in sensitivity of at least 10%.
