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Three MM cell lines were chosen for our investigation based on their NF-κB index [ 16]: EJM with the highest NF-κB index, RPMI-8226 an interim index, and H929 with a low level of NF-κB activity.
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We used all existing previously coded deficits to establish an interim frailty index, whose purpose was to help provide cut-points for the remaining variables.
The value of the individual variable that corresponded to 0.2 on the interim frailty index, i.e. the value of the variable at which, on average people had a frailty score of 0.2 or higher, was denoted as that deficit's cut-point.
In addition, cut-points can be difficult to apply across a sample that covers many ages, as the effects of continuous traits can be age-specific.[ 28] Our approach derived cut-points based on the "interim frailty index" procedure described above.
were plotted against interim frailty indexes, similar cut-points to their published cut offs were found (data not shown).
Leary (1985, p.47), commenting on a related matter, warned that "what began as an interim solution (site index) to a difficult problem (geocentric approach [to site productivity estimation]) should not now be called the solution to the original problem" and his caveat applies equally to modelling.
Because iMatter was theoretically grounded, situated within policy, developed by staff and modified through a process of consultation over a series of robust cycles [Snowden and Macarthur, validation of the NHS Scotland Employee Engagement Index: Interim Report, Unpublished] the results of this study allowed trustworthy interpretations to be made.
[UK] PeoplePerHour.com, the online marketplace for freelancers, has closed an interim funding round with Index Ventures who participated on equal terms with existing shareholders.
They have yet to be released; in the interim, Mr. Tuerff said, the index can serve as a tool for the public.
This similarity may be due to the fact that health profiles of 5L are mapped unto the 3L to derive its index score using an interim scoring " EQ- 5D 5L Crosswalk Index Value Calculator" [ 13].
Multiple linear regression models were used to assess the difference in EQ-5D-5L index (calculated using an interim algorithm) and EQ-visual analog scale (EQ-VAS) scores across survey language (Chinese vs. English, Malay vs. English, and Malay vs. Chinese).
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