Sentence examples for interim dose from inspiring English sources

Yet, in the conditioned place preference paradigm, while both ultra-low (0.03 and 0.3 ng/kg) and higher (30 ng/kg) naltrexone doses blocked the acute rewarding effects of oxycodone, an interim dose (3 ng/kg) was without effect [6].

Half of the subjects enrolled received an interim booster dose at year 5 (boosted) group, whereas the other half of the subjects enrolled did not (unboosted group).

At the interim analysis, doses may be dropped from the trial, or the trial may be stopped altogether.

Low PPV could make it difficult to modify the therapeutic plans with interim PET-adapted dose escalation or high-dose chemotherapy in poor responders.

The cohort expansion used in dose-finding is adaptive, based on the interim comparisons between each dose and placebo.

After 18 patients had entered the study and received the recommended dose, an interim analysis was to be performed to determine the objective response rate (CR+PR).

After an interim safety analysis the capecitabine dose was reduced to 1500 mg/m PO BD d1-7 (C1500) with doses of the other agents unchanged.

After a prespecified interim analysis to assess LY2605541 dose conversion and adjustment, this was changed to 7 nmol LY2605541/unit of GL.

The p-value for the one-sided t test between these two doses in the interim analysis was p1 = 0.206.

Besides the planned analysis during the dose escalation, no further interim analyses are planned.

An adaptive trial design would permit enrichment of the responder population as well as more efficient randomization of patients to dose groups based on interim assessments of efficacy and futility status against a priori boundaries.