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Antibodies recognizing the M1 muscarinic acetycholine receptor have also been associated with the development of CHB, and in vitro studies suggest a functional role for these antibodies through binding to and interfering with the function of their target in the neonatal myocardium [ 34, 35].
Such agents exert their effects by inducing changes in those genes or by interfering with the function of the proteins that the genes encode.
Novobiocin and Coumermycin were also shown to cure drug resistant plasmids from S. aureus by interfering with the function of DNA gyrase which is required for proper replication and maintenance of plasmid.
Surface-associated capsular polysaccharides (CPSs) protect bacteria against phage infection and enhance pathogenicity by interfering with the function of the host innate immune system.
As PEtOH builds up, it starts interfering with the function of critical proteins on nerve cells, causing the nerves to become more excitable.
This reinforces the belief that drug molecules, at least partly, work by interfering with the function of multiple targets within the cellular milieu.
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In rare cases, infantile hemangiomas may interfere with the function of tissues or organs.
Excessive or prolonged use engenders toxic side effects: it interferes with the function of hemoglobin, the oxygen-carrying pigment of the blood.
Because such particles could interfere with the function of the thyroid gland, it said, iodine tablets were being issued to infants, children and pregnant mothers in the region.
This prospective study was directed at determining whether vincristine treatment interferes with the function of the medial olivocochlear bundle.
Evidence from this study suggests that the R1746Q mutation interferes with the function of CEP290 to maintain the ciliary diffusion barrier and disrupts the integrity of the molecular composition in the primary cilium, which may contribute to alterations in neuroarchitecture.
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