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However, it is still a challenge to control the toxicity without interfering with efficacy.
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Thus, binding of stampidine to plasma proteins is not a phenomenon that would interfere with efficacy.
If the dose reduction interferes with efficacy of pain control, it is recommended to add adjuvant therapy such as steroids, neurontin, or low dose tricyclic antidepressants (Cherny et al 2001).
Although we consider this unlikely, the application of 15 single-pulse and 15 paired-pulse stimuli at approximately 0.1 Hz might have had an "occlusion effect" interfering with the efficacy of subsequent associative HFS protocols to induce spike-timing dependent plasticity.
However, such approaches often results in limited success either at experimental phase or in clinical trials, mostly due to mutual cross-talk of PI3K and MAPK pathways interfering with the efficacies of these inhibitors11.
Reducing this toxic effect without interfering with the treatment efficacy of cisplatin and gentamicin is one of the main goals in otoprotective research.
In spite of the purported efficacy in each active constituent, the coexisting constituents in the herbal extract might interfere with the efficacy and safety and affect the pharmacokinetic properties of active constituents.
Experiments were conducted using media without serum, which was shown to interfere with inhibitor efficacy in a pilot run.
Our analysis strongly indicates that dexamethasone interferes with the efficacy of both TTFields and BPC chemotherapies, the latter of which consisted largely of alkylating chemotherapies.
Individuals with GH gene defects, however, may form GH antibodies that interfere with the efficacy of exogenous recombinant GH (rhGH) therapy.
(An uncited reason was revenge for Democrats' blocking of Mr Bush's nominees).Fed officials can ignore politics as long as it does not interfere with the efficacy of monetary policy.
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