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The results obtained by using organ cultures demonstrated direct effects of E2 and MPA on the proliferation and differentiation on human breast tissue without the interference with the systemic effects found in vivo.
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In the present study, we excluded potential prognostic effects as well as interference with other systemic therapies by using a well-established in vitro assay (ATP-TCA) for primary tumour cells (Andreotti et al, 1995; Cree et al, 1996; Kurbacher et al, 1996; Hengstler et al, 1999b; Konecny et al, 2000) in a consecutive series of 53 primary breast cancers.
This latter route provides direct access of the protective agents to inner ear structures while avoiding systemic side effects and interference with the antineoplastic activity of cisplatin [ 16].
Symptoms like estrus cycle irregularities, reduced reproduction rate, or delayed sexual maturation may be due to systemic toxic effects, for example seen as decreased body weight, but also due to interferences with the endocrine system [25].
"I am more than open to, and receptive to, dealing with the systemic problems," she said.
This solution eventually mixes in with the systemic circulation, contributing to elevated systemic potassium levels.
These include regulation of intestinal microbial homeostasis, maintenance of the gastrointestinal barrier function, interference with the ability of pathogens to colonize [16], [17], [18], [19], [20], [21], [22] and finally modulation of local and systemic immune responses [23].
We had enough of interference with the Baath Party".
Interference with capital movements is generally considered a lesser evil than interference with the free flow of trade.
"Ocean fertilisation involves huge interference with the ecosystem.
That may be government interference with the free market?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com