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Various forms of interference with the blood supply may affect the nail matrix and produce irregular growth of the nails.
Sudden interference with the blood supply to the heart muscle, as by a thrombosis in a coronary artery, causes damage to the muscle with resultant diminution in its contractile force.
Fracture may cause necrosis by interference with the blood supply of the bone in the immediate vicinity of the break or by damage to larger vessels that furnish a large part or all of the nutrition to one of the fragments.
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Moreover, apo(a) has a high homology with plasminogen and in vitro studies reported interferences with the blood clotting and fibrinolytic cascades.
In mixing experiments using human whole blood, we were able to fractionate cancer cells without interference from the blood cells.
Our finding of significant decrease of Taq DNA polymerase activity in samples supplemented with blood and even more with blood and 1,2-propanediol, and removal of this inhibitory effect after addition of trehalose suggest that trehalose acts by protecting the enzyme from negative interference of the blood inhibitors.
On the other hand, local effects of ACS are probably best reflected by wound dehiscence secondary to direct pressure on the wound, as well as interference with local blood supply.
The immunosuppressive effect of these drugs is primarily due to their interference with white blood cell chemical signaling that allows them to provide a coordinated immunological response.
Current therapeutic antiangiogenic biologics used for the treatment of pathological ocular angiogenesis could have serious side effects due to their interference with normal blood vessel physiology.
Current therapeutic anti-angiogenic biologics used for the treatment of pathological ocular angiogenesis such as in diabetic retinopathy and wet macular degeneration often lead to detrimental side effects due to their interference with normal blood vessel physiology.
For example, new bone formation may be stimulated by the effects of trauma or interference with blood supply or be associated with the repair processes which any follow these events.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com