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To date, however, there have been no studies that have explored the role of PKD2 in vivo, although there are several in vitro studies using RNAi (RNA interference) techniques in cell lines that have proposed important non-redundant functions for PKD2.
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As knockdown of miR-296-3p miR-296-3p miR-296-3pactuallyressincreasedhen down-expressed ICAM-1 by thexpressionRNA interference technique in M12-anti-miR-296-3p cells, getting in a stable cell line M12-anti-miR-296-3p+shICAM-1 (Supplementary Figure S8, right), weich reversely reduced thenNK cell cytotoxicities to the similar levels as those in M12-ctrl cells.
In this section, we compare and evaluate the MN interference techniques and discussed in earlier sections, through system level simulations.
Functional interference techniques actively intervene in neural processing, for instance by permanently or transiently changing (often disrupting) the neural mechanisms at work.
A powerful way to distinguish pre-duplication and post-duplication targets would be by comparison to Cdx target genes in non-vertebrates; however, for this, functional interference techniques will be needed in systems such as annelids, echinoderms, and cephalochordates [ 47].
With the experimental occlusal interference technique used in this study, the occlusal height of the right first mandibular molar could be raised by up to 0.75 mm using the whole crown covered with resin.
Such processes are indeed affected at the physiological levels, as a knock down of WRN-1 protein expression by the RNA interference technique results in various developmental defects, including small, dumpy, ruptured, transparent body, growth arrest and bag of worms [ 33].
The only non-invasive interference techniques that can be safely used in human neuroscience are transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS).
Invasive interference techniques, including cooling, microstimulation, and lesioning, are mainly used in animal studies.
We generated caveolin-1 and -2 knockdowns in MLE-12 cells by using RNA interference techniques.
Hundreds of target genes were inactivated in each query-gene background by using RNA interference techniques, see also [13].
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