Sentence examples for interference targeting from inspiring English sources

None of the transformants expressing antisense or RNA interference targeting QHB displayed a phenotype.

Huntingtin-lowering strategies include antisense oligonucleotides and RNA interference targeting mRNA, and zinc finger transcriptional repressors and CRISPR-Cas9 methods aiming to reduce transcription by targeting DNA.

We compared radiosensitivity in a "single-hit" cell line with TP53 mutation converted to "double-hit" using RNA interference targeting FHIT.

Using GSTP1-deficient MCF-7 cancer cells and siRNA interference targeting GSTP1 in HaCaT keratinocytes expressing either wild-type or mutant HPV-16 E7, we uncovered a pivotal role for GSTP1 in the pro-survival program elicited by its binding with HPV-16 E7.

Furthermore, in a recent small-molecule screen, Isojima and colleagues found that a common feature of compounds causing an increase in circadian period was inhibition of CK1δ/CK1ε activity, and RNA interference targeting either kinase lengthened period in human U2 osteosarcoma cells, although reducing expression of CK1δ by RNA interference had a larger effect than knocking down CK1ε [25].

Furthermore, administration of polyI C exacerbated, whereas RNA interference targeting TLR3 ameliorated, the arthritis.

Two metal cylinders are placed in the imaging area to simulate the interference targets inside the building.

Moreover, RNA interference targeted on Beclin1 comfirmed YM155 (12.5 nM -induced autophagy was depenM -inducedclin1 expression.

In experiments where SIRT1 siRNA transfections were applied, two siRNAs obtained from Life Technologies (Saint Aubin, France) were used to confirm the specificity of the interference targeted to SIRT1.

These data are overall in agreement with those previously obtained by a case-by-case approach performed on chromosome 1 genes, and quantitatively with those obtained by "high-throughput phenotyping using parallel sequencing of RNA interference targets" (RIT-seq).

Moreover, all 101 CDSs but two (Tb10.61.1810 and Tb927.7.2990, code name in our study: T217 and T320) were also included in a global approach of "high-throughput phenotyping using parallel sequencing of RNA interference targets" (RIT-seq) developed after the start of our study [ 8].