There was no previous surgical interference before presentation in 13 of the cases, but a previous bilateral adductor tenotomy was implemented 12 months before presentation in two cases (one patient) while the other case had a previous unsuccessful valgus osteotomy to correct for unilateral developmental coxa vara which was fixed by plate and screws.
On the other hand the full-length HCMV protein antigens are unlikely to be degraded rapidly and may also initiate various intracellular signalling events leading to the interference of presentation of epitopes from other antigens [50], [51].
Interference with peptide presentation by HLA-DQ2, for example, by the use of peptide blockers, is a possible treatment strategy for such HLA-associated disorders.
SPI-2 encoded proteins like SifA, SspH2, SlrP, PipB2, and SopD2 were found to be important for the interference with antigen presentation, whereas SseF and SseG contributed to a lesser extent to this phenotype [41].
Several groups have shown that tobacco smoke as well as individual smoke components induce physiological and structural changes, e.g. reduction of mucociliary clearance [2], [3], and dysregulate specific elements of immune function, e.g. inhibition of the respiratory burst and phagocytosis [4], [5], [6] and interference in antigen presentation [7], [8].
The current study replicated Shimojo et al.'s (2003) design, whilst controlling for potential inter-stimuli interference in central presentations.
Miscuing refers to the fact that responding to A is impaired after one B-US presentation whereas interference is the impairment of responding to A after presentation of C-US pairings.
Epitope sequences, assembled in tandem in the above mentioned order, had GPGPG spacers at C and N termini, to avoid the creation of junctional epitopes and interference with processing and presentation [54].
Epitope sequences, assembled in tandem in the above mentioned order, had GPGPG spacers at C and N termini, to avoid the creation of junctional epitopes and interference with processing and presentation [56].
A well-known effect of blocked presentation in interference tasks (e.g., Stroop effect) has been reported elsewhere (for a recent report, see [ 42].
