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Taking advantage of RNA interference methods to specifically silence GSK-3α and/or GSK-3β in 22Rv1 prostate cancer cells, we have examined the specificity of commonly used anti-pSer and anti-pTyr GSK-3 antibodies.
Whereas the simplest approach, conceptually, would be to use antisense or RNA interference methods to knock down the pathogenic RNA itself, such approaches remain difficult due to the general inability of such agents to traverse the blood brain barrier.
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The sequence information of ω-secalin genes with expression activity will be helpful for improving the processing quality of wheat with 1BL/1RS translocations by using RNA interference method to silence the expression of the ω-secalin genes.
To conduct the study, Dimopoulos' team used an RNA interference method to "knock down" the genes of the Imd pathway.
To analyze the function of endogenous expression of autotaxin by breast cancer cells in bone metastasis formation we used the RNA interference method to establish a series of three clones of 4T1 cells with stably down-regulated autotaxin expression (4T1-siATX), together with three control 4T1 clones with unaltered expression of autotaxin (4T1-sbATX) (Figure 4C).
With targeted and rapid control over specific populations of cells, optogenetic technology is a well-matched interference method to couple with high-resolution electrochemical detection.
We developed an in vitro model of SMA using a lentiviral RNA interference method to downregulate the Smn protein level of isolated mouse spinal cord MNs, and have now used this model to analyze changes in the autophagy process in Smn-reduced MNs.
There are unique requests for both, however, and for specific interference methods supposed to have taken place on the respective platforms.
For successful deployment of such a strategy in the two-tier LTE cellular network, we examine the severeness of four cross-tier interference scenarios under hybrid spectrum arrangement and propose the interference mitigation methods to alleviate the residual significant interferences among them.
Besides that, the loopback signal created from the transmitting antenna at the selected relay, which is regarded as loopback interference, thus requires additional energy to apply interference cancellation methods to mitigate this problem.
Most recent studies on the frequency allocation and capacity analysis for small cells are using co-channel and orthogonal frequency allocation schemes in the single cell scenario, which apply the interference cancelation methods to improve the network capacity.
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