Sentence examples for interference machinery from inspiring English sources
Transcriptional silencing in fission yeast requires several core components of the RNA interference machinery.
Access to RNA interference machinery located in the cytoplasm is often overlooked, but must be considered when designing the next generation of siRNA delivery strategies.
Both the biogenesis and action of miRNAs rely on components of the RNA interference machinery, with several distinctions (for a comprehensive review see [6]).
Dicer is a key endonuclease in the RNA interference machinery that cleaves precursor microRNAs (miRNAs) into mature miRNAs during miRNA biogenesis [1], [2].
Although these findings need to be further confirmed, interfering satBaMV may potentially manipulate the RNA interference machinery to generate BSL6-specific siRNAs that can target and regulate host genes and lead to downregulation of BaMV.
A loss of function in components of the RNA interference machinery in S. pombe, Drosophila and mouse results in an abnormal distribution of HP1 and defects in heterochromatin formation [99] [105].
Small interfering RNAs (siRNAs) have been extensively considered as perspective RNA targeting therapeutics since the discovery of cellular RNA interference (RNAi) machinery.
Though, the biggest reason to not have cell phones in hospitals (interference with machinery) has been described as "merely an irritation and ultimately harmless to the patient".
Apparently, these Made1-related structures are recognized by the RNA interference enzymatic machinery and processed to form 22 bp mature miRNA sequences.
This would provide ample opportunities for the processing of MITE hairpins by RNA interference enzymatic machinery, which is known to play a particularly important role in plant gene regulation [51].
Therefore, we propose a model whereby Made1 insertions into transcriptionally active genomic regions would yield viable pri-miRNA structures that would be processed into mature miRNA sequences by the RNA interference enzymatic machinery.
