Channelled into the vitamin B1 biosynthesis of S. aureus, the pyrophosphorylated bacimethrin exchanges HMP-PP to give a non-functional TMP derivative, that may subsequently interfere with the function of TPP-dependent enzymes [7], [25], [26].
In rare cases, infantile hemangiomas may interfere with the function of tissues or organs.
The ability to specifically interfere with the function of proteins of pathological significance has been a goal for molecular medicine for many years.
Fatty acid derivatives can interfere with the function of the cell and ultimately lead to its demise through lipoapoptosis, the consequences of which are gradual organ failure.
The result is the creation of an abnormal protein that allows the uncontrolled production of white blood cells, which can interfere with the function of other organs in the body.
This overlap between HR-/HER2+ breast cancer and the immune system opens up some exciting therapeutic opportunities, particularly because previous research has already produced FDA-approved drugs that interfere with the function of this specific pathway.
Since this experiment, the researchers have found 30 other variants of the MTHFR enzyme and tested about 15 of them, "and more than half interfere with the function of the enzyme, producing a hundred-fold range of enzyme activity.
In early leaves, miR319-targeted TCP transcription factors interfere with the function of miR164-dependent and miR164-independent CUC proteins, preventing the formation of serrations in A. thaliana and of leaflets in C. hirsuta.
Compounds that interfere with the function of every protein expressed by the virus have been characterized, but only inhibitors of the NS3 protease, the NS5A replication complex protein, and the NS5B RNA-dependent RNA polymerase are of clinical relevance.
If only one lung is transplanted, however, the patient's own diseased lung may interfere with the function of the graft by robbing it of air and directing too much blood into the graft.
And this isn't because the chemicals interfere with the function of any of our organs: They seem to interfere with the friendly bacteria in our gut.
