Sentence examples for interfere the expression from inspiring English sources

This sequence was not homologous to Tiam2, a guanine nucleotide exchange factor-GEF with significant identity to Tiam1, or any other known gene as determined by a BLAST search [22] and was not able to interfere the expression of Tiam2 (data not shown).

MicroRNAs (miRNAs) are a large class of ~ 22nt long non-protein-coding RNAs that post-transcriptionally interfere the expression of their target genes by binding to the 3'-untranslated regions (3'UTR) [ 1].

To further confirm the receptors through which HMGB1 exerts its effects, we used TLR2−/− and TLR4−/− mice [ 30] and a neutrophil-like HL-60 cell line transfected by TLR2, TLR4 or RAGE siRNA to interfere the expression of corresponding receptors at genetic level to validate our findings.

Open image in new window Figure 4 Transfection with miR-875 and miR-3144 inthefexpressionxpressiof of endogenous E6. (A) The expression levels of miR-875 or miR-3144 by qRT-PCR in SiHa cells transfected with miR-875 or miR-3144 expression vectors, SiHa cells transfected with empty vectors (Vector), or untreated SiHa cells (Mock).

Additionally, to interfere with the expression of the Beclin1 gene in cells we also transfected a Beclin1 siRNA (small interfering RNA) vector into HeLa cells.

These data suggest that exposure to hypergravity may interfere with the expression of selected cerebellar proteins.

These results suggest that increasing cognitive load during a pain-eliciting task may interfere with the expression of communicative pain behaviors in high catastrophizers.

The experimental model above was used to measure the repression effect on exogenous E6, we further investigated whether miR-875 and miR-3144 could interfere with the expression of endogenous E6 oncogene.

By using the luciferase reporter, synthetically constructs and cultured cells, we show that miR-875 and miR-3144 causeausilencinging effect of target reporter and interfere with the expression of E6 oncogene.

Moreover, the differentiation processes were shown not to interfere with the expression of the reporter gene.

To interfere with the expression of multiple cytosolic HSP90 isoforms, we cloned four regions of HSP90 with differing sequence identity across the four cytosolic isoforms.