Neural stem cells will become an essential instrument to unraveling basic questions related to brain development, providing a unique cellular interface with tissue-engineering approaches and working toward the promise of medical breakthroughs.
The surface forms a biologically active hydroxycarbonate apatite (HCA) layer, which provides the bonding interface with tissues.
"Nanowire Nanoelectronics: Building Interfaces with Tissue and Cells at the Natural Scale of Biology". Pure and Applied Chemistry 85 (5) (January 11).
The authors concluded that "printed droplet networks might be interfaced with tissues, used as tissue engineering substrates, or developed as mimics of living tissues".
This connective tissue layer can be identified on the OCT image by its clear interface with bone tissue and by the banding pattern consistent with polarization changes due to the tissue birefringence.
"The materials that we are using are fully organic, and the structures themselves are designed to interface with neural tissue," Anikeeva says.
Understanding axonal formation and contact guidance are of critical importance for the design of materials that interface with neuronal tissue.
Ultimately bioengineered solutions using materials require some haptic interface with biological tissue and by colocation, cells as well.
Nanomaterials have the unique ability to interface with neural tissue in the nano-scale and are capable of influencing the function of a single neuron.
We describe a set of software and hardware tools to interface with neural tissue, in order to transmit visual information encoded into a bioinspired neural-like form.
