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Interestingly, cold and heat shock induce nucleolin mRNA concomitantly to enhanced mRNA expression of the heat shock protein 70, thus suggesting that surface nucleolin induction also occurs in response to an environmental insult.
Interestingly, cold induces a site-specific hypermethylation at these non CG sites.
Interestingly, cold induced fructan content increases were much higher in core Pooideae (0.8-1.2 0.8-1.2han in B. distachyon (0.2-0.3 fold).
Interestingly, cold- and wound-responding genes were enriched in genes induced by competition, whether they belonged to repressed or induced gene sets.
Interestingly, cold adaptation of Bacillus subtilis has been reported to be mediated by RNA-helicase [ 37], although the role of adenine methylation in the DNA-helicase gene remains unknown.
Interestingly, cold shock proteins and DBRHs have been suggested to work together, with helicases opening double-stranded structures and cold shock proteins binding to the single-stranded end products, their combined activities preventing the formation of unfavourable structures (Hunger et al., 2006).
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Interestingly, cold-induced shivering by muscle contraction stimulates irisin secretion to levels that are nearly comparable to those induced by exercise (Lee et al., 2014), suggesting that irisin may link exercise to cold-induced thermogenesis and promote browning of human neck adipocytes and thermogenesis in concert with FGF21 during cold-exposure (Lee et al., 2014) (Fig. 1).
Interestingly, cold-adaptation increased the abundance of S-adenosylhomocysteine hydrolase (SAHH), an NAD+ dependent enzyme and component of the methionine-cysteine transulfuration pathway that generates cysteine used to synthesize GSH [ 32].
Interestingly, cold-exposed normal subjects and patients suffering from pheochromocytoma (a norepinephrine-secreting tumor of the adrenal gland) show increased BAT by PET with an anatomic distribution similar to that of mice – that is, closely associated with the aorta and its main collaterals (Kuji et al., 2008; Saito et al., 2009).
Interestingly, several cold related proteins were among the most abundant ESTs in the cold-acclimated library but were not represented among the most abundant ESTs from oat grown under optimal conditions.
Interestingly, after cold, salt, ABA, salt and air-dried treatments, lateral roots and root tips of transgenic rice seedlings showed a distinct pattern of OsADF3 promoter-driven GUS expression.
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