As the annotation functions from GO and KEGG are both constructed in tree structures, users may select interested functions one by one or directly select a whole branch from the annotation tree.
Darwin, of course, was always more interested in function, and his thesis of natural selection was explicitly directed at the problem of explaining functional adaptation.
His white frames fold up so cleverly, though, it is clear that Mr. Kimmel is as interested in function as in paying homage to the '80s, a decade he remembers fondly despite being in roughly the sixth grade.
It isn't a standout "look at me" piece of technology, which is good if you're more interested in function and classic design than showing off, and is comfortable to wear.
It may be that biologists are happy with high-quality information retrieval tools, and are not actually very interested in function prediction at all.
In addition to use a list of genes for filtering, ChIPseek also offers built-in functional annotations downloaded from GO and KEGG [ 28, 29] which allow users to generate gene lists based on their interested biological function or pathways.
In this study, GOOD is presented as a gene-oriented comparison platform of functionalities based on orthology for researchers to derive interested molecular functions from experiments in model organisms to speed up the process of functional annotation.
Due to the considerably increased number of genes differentially regulated between light and darkness in Δblr1, Δblr2 and Δenv1, we were interested, which functions were targeted by this regulation.
His research for his dissertation was on fly development and neurobiology, but, he said, "I was almost instantly much more interested in the function of the whole fly than the more mechanistic but probably more well-posed problems of how the little axons grow to the brain".
He eventually became interested in brain function and undertook research on animals and then on human epileptics whose brains had been "split"—i.e., in whom the thick cable of nerves (the corpus callosum) connecting the right and left cerebral hemispheres had been severed.
