Nanofibrous nerve guides have gained huge interest in supporting the peripheral nerve regeneration due to their abilities to simulate the topography, mechanical, biological and extracellular matrix morphology of native tissue.
Because infants and young children with IS are unable to perform perimetry, confrontation testing in which small toys of interest are held in the peripheral field to see if any eye movement occurs is recommended as a qualitative assessment to identify patients who may have pVFD and may require additional testing [ 46, 47].
The failure of the main classical central nervous system targets against obesity (i.e. serotonin transmission-based drugs or cannabinoid receptor antagonists) has prompted interest in the targeting of safer peripheral mechanisms controlling appetite and energy expenditure (Crespillo et al., 2011; de Fonseca, 2008).
The main interest in using peripheral blood for potential classifiers of antidepressant, antipsychotic, and mood stabilizer response, as opposed to brain tissue samples, is the relative ease of acquisition and the practical utility of blood samples.
Outside the sports arena, observers came to perceive FIFA as a moneymaking venture with merely a peripheral interest in the welfare of the game itself.
There has been increasing interest in the use of whole genome peripheral blood gene expression in a wide range of conditions to attempt to identify both novel mechanisms of disease and transcriptional biomarkers.
Of interest, the peripheral blood IFN gene signature can already be observed in the preclinical phase of the disease [ 51].
Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing.
There has been growing interest in the use of proteomic methods on peripheral blood plasma to rapidly profile protein markers that link expression of the genome with the disease process (Cahill, 2001; Plebani, 2005) and to discover novel biomarkers of therapeutic response (Smith et al, 2006).
There has been growing interest in the use of proteomic methods on peripheral blood plasma to rapidly profile protein markers which link expression of the genome with disease processes (Cahill, 2001; Plebani, 2005) and to discover novel biomarkers of therapeutic response (Smith et al, 2006).
