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Proximity and interconnection of both compartments argues for micro-aspiration as the main process leading to bacterial immigration from the upper to the lower airways.
These results are consistent with a close interconnection of both enzymatic pathways as proposed before [ 25, 29, 30].
The signal transduction network in Figure 2, though partial and non-exhaustive, highlights the strong interconnection of both signalling pathways.
For example, recent studies in P. pastoris have hinted an interconnection of both the carbon metabolism [ 58] and the cellular redox state [ 59] with protein production and secretion.
In addition, the close interconnection of both trajectories is also mirrored by mutational studies that identified two conserved amino acids in the I-helix region of AOS.
Besides their common role in cellular nutrient supply and their shared terminal end point, the interconnection of both pathways is also demonstrated by the fact that autophagosomes fuse with early or late endosomes [ 9].
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The two examples above show that effective policy and action can only be grounded in careful and comprehensive identification of relevant elements and in depth understanding of interconnections both at local as well as at national and international levels.
In this paper, we consider a hierarchical network system which is an interconnection of dissipative subsystems and identify both subsystems and network structure, called network system, preserving the dissipativity properties.
Thus, our combined OCT and 1H-MRS data may suggest an interconnection of MS-associated neurodegeneration in both parts of the visual pathway.
21, 34 Removal of the guest molecules gives access to a 3D open structure in both materials which is a product of the interconnection of 1D pores.
"But... you get this terrible interconnection of unintended consequences".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com