It is important to emphasize that Treg and Th17 developmental programs are reciprocally interconnected: upon T cell receptor (TCR ) stimulation, naive T cells can be driven to express FOXP3 and become Tregs, if TGFβ is present.
E. G. Maiorov et al. identified interconnected markers for T-cell acute lymphoblastic leukemia (T-ALL).
This uncertain fuzzy large-scale system consists of N interconnected T-S fuzzy subsystems, and the parametric uncertainties are unknown but norm-bounded.
The T-S fuzzy model consists of N interconnected discrete-time Takagi-Sugeno (T-S) fuzzy subsystems, the decentralized control scheme is adopted and the communication links between the subsystem and controller are assumed to be imperfect, that is, data packet dropouts occur intermittently, which is often the case in a network environment.
Self-aligned T-NT arrays interconnected along the sidewalls via thin enclosing membranes can also be observed from the top and side view (pointed in Figure 2b,c).
The SSR problem of the T-G units interconnected with a series compensated transmission line has been recognized for many years and extensively studied [4].
Consider a class of linear large-scale systems with interval time-varying delays composed of N interconnected subsystems i = 1, N ¯ of the form x ˙ i ( t ) = A i x i ( t ) + ∑ j ≠ i, j = 1 N D i j x j ( t − h i j ( t ) ), t ∈ R +, x i ( t ) = φ i ( t ), ∀ t ∈ [ − h 2, 0 ], (2.1).
The serine-threonine kinase, mammalian target of rapamycin (mTOR), is a candidate gene as a master regulator of CD4+ T cell differentiation and metabolism [ 94], which are interconnected.
However, as it was recently pointed out by Maiorov and colleagues (2013), the expression of some genes might not vary in the T-ALL, but, instead, these genes may be interconnected with highly differentially expressed ones [ 125].
The main findings of this study are that pleiotropic genes in T-cell-associated diseases formed a module of highly interconnected genes.
Iteratively, one target gene at a time, we can construct the overall dynamic equations of transcriptional regulatory network of inflammation, which are interconnected through the regulations ∑ i = 1 L b ^ i ⋅ x i [ t ] of TFs.
