The daily environmental assaults posed to normal pulmonary and cardiovascular cells can exert multiple, complex, and often interconnected stress responses.
Genome level transcriptional profiling of a given cell, tissue, or organ provides a map of interconnected molecular pathways and reflects coordinated response of their various components to a given physiological condition.
Autophagy and apoptosis are important and interconnected stress-response mechanisms.
Autophagy and apoptosis are two important and interconnected stress-response mechanisms.
Analysis of the defense and hormone response subnetworks indicates that hormone response is interconnected with defense response.
Although the roles of hormone and defense response genes have been discussed in the four previous reports [ 5, 10- 12], our network analysis further indicates that hormone response is interconnected to defense response in citrus when challenged by the HLB bacteria.
Moreover the positive correlations between the BOLD signals in pons and midbrain with those in hypothalamus, thalamus and amygdala support the notion that activation in these regions reflects an interconnected pathway, the response of which is modulated in part by DA and serotonin neurotransmission.
Plant survival is dependent upon a network of interconnected cellular stress response systems that involve the activation of a wide range of transcriptional factors; this network is challenged by global climate changes such as global warming, which makes heat stress a significant concern [ 4– 7].
The GUI visualizes the responses as interconnected boxes located above the search engine's input box.
The report lists five core "pillars" which underpin the its various "interconnected and mutually reinforcing responses" — all of which are in turn aimed at forming a holistic overarching strategy to attack the problem from multiple angles and time-scales.
It may be surmised that increased mitochondrial aerobic metabolism and inflammatory responses are interconnected and support the functionality switch of astrocytes, from neurotrophic to neurotoxic with age.
