We partitioned this network into areas that are highly interconnected by interactions by applying the Markov graph clustering algorithm (MCL [ 23]; Fig. 1).
Analysis revealed that these proteins are highly interconnected (protein protein interactions p value 5.66E−15) (Fig. 5) and significantly enriched for KEGG fatty acids-related pathways (Peroxisome, PPAR signaling, Fatty acid metabolism) and xenobiotics metabolism.
By iteration of equation (1), we can construct the whole protein-protein interaction network, which is interconnected through the interactions of ∑ i = 1 N b i x i (t ) and ∑ i N ∑ j = 1 N c i j x i j (t ) in equation (1) for all proteins.
Nevertheless, little is known about how the two processes are interconnected, as the interaction between the IFT complexes and their molecular motors is still poorly understood.
As expected, the volatiles that clustered together on the HCA were interconnected by positive interaction represented with blue lines in CNA.
As shown in Fig. 6, these common proteins form a highly interconnected protein-protein interaction network among themselves, thus highlighting an orchestrated activation of the growth-promoting pathways in old WT mice.
Here, differentially expressed molecules [ideally identified using a significance threshold that accounts for multiple hypothesis tests (Storey & Tibshirani, 2003)] are grouped into sub-networks that are highly interconnected in an interaction dataset.
It interacts with both the loop III and the loop I. Loop III genes are closely interconnected via the interactions between PRR9, LHY and CCA1, and the interaction between CCA1 and PRR7.
At the regional scale, these influencing factors are interconnected, and the interactions between them can also affect the single parameter of Budyko-type equations' estimating.
Compound 1 possesses an infinite 1D ladder-like chain structure with [Zn(H2O 6]2+ trapped in the pores, which is further interconnected by π⋯π interactions to lead to a 2D supramolecular architecture.
