These findings indicate that the aforementioned canonical pathways are all interconnected in the regulation of mRNA translation and mitochondrial metabolism.
In the context of increasingly interconnected, rapidly changing and uncertain political, economic, and social conditions, this implies an urgent and strong need for capacity and resilience building in coping with and managing global systemic risks across all levels and regions.
Almost all of the genes encoding these WRKYs were found interconnected in the co-expression network.
In Ref. [29], the tearing and interconnecting approach of finite element methods is used in the context of isogeometric analysis, and the numerical tests (in absence of any theoretical study) suggest almost optimal (with a logarithmic factor) convergence rates of the proposed isogeometric tearing and interconnecting method.
We are all interconnected in the economy".
How are these correlated reactions interconnected in the network?
In addition, the selection of IL-1, of leptin, and of β-endorphin, among the wide range of immunomodulatory factors present in breast milk and interconnecting the neuroendocrine and immune systems, has been made in the context of the present study mainly for convenience and not according to solid scientific reasons.
The network analysis of three molecules NPM1, RKIP and GRP78 by MetaCore program allowed the addition of two proteins in the context of systems biology, HSPB1 (HSP27) and nucleolin (NCL), interconnected to at least three transcription factors, ESR1, STAT3 and SP1, and downstream of EGFR receptor pathway, classically known as modified in GBM (Fig. 6).
Thus, these genes are preferentially interconnected among themselves with fewer connections to other genes, which defines them as a module in the context of the Arabidopsis genome.
Another important characteristic is that functionally related nodes tend to be highly interconnected and co-localize in networks, thereby forming modules [ 7, 14] (Table 1).> In the context of disease, disease-associated genes identified by omics studies can be computationally mapped on to models of the human protein-protein interaction (PPI) network.
