Sentence examples for interactions validating from inspiring English sources

Concluding, in the proteasome, ribosome and spliceosome proteins which carry those domains tend to shape stable structures which are mostly governed by self domain interactions, validating the presence of self interactions in our predictions.

All of these interactions validated the effectiveness of using the contrast test.

Overall, 47 different drug-gene interactions validated (Table 2), and in only two cases; isotretinoin vs. SMAD3 (CMAP and fibroblast screen; Fig. 1) and dexamethasone vs. ITPR1 (CMAP and CRE) was the same interaction identified by more than one method (Fig. 2).

We have determined the validation rate of these approaches for 76 diseases (i.e., in vitro fibroblast mRNA increase); for the Connectivity Map, approximately 5% of tested putative drug gene interactions validated, for causal reasoning engine knowledge base the rate was 10%, and for the targeted drug screen 9%.

Although the focus of this paper is on the interaction between TTP and CIN85, the other interactions validated may be of physiological importance.

Only interactions validated with strong evidence (reporter assay, Western blot or qPCR) were included.

(XLSX 326 kb) Additional file 11: The miRNA/target interactions validated by PAREsnip program.

However, there still were some interactions validated by literature evidences absent in the constructed subnetwork.

The miRTarBase (mirtarbase.mbc.nctu.edu.tw) represents the collection of 4,270 manually curated miRNA-target interactions validated experimentally between 669 miRNAs and 2,533 target genes among 14 species [ 26].

From this dataset we obtained two PPI subsets with increasing confidence: a set of 28 971 interactions validated by at least one 'binary' experimental method [binary as defined in (De Las Rivas and Fontanillo, 2010)]; a set 6033 interactions validated by at least two experimental methods, one of them binary.

Comparing both networks, we observed that approximately 35.7% (or 30 out of 84) of the interactions validated in the adipose tissue were also validated in the liver co-expression analysis (Additional file 7: Table S5).