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To the model we individually added three two-way interactions, screening approach*tool, screening approach*intervention, and screening tool*intervention and compared the result with a model without interactions.
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Thus, Y2H can be adopted for domain-motif interaction screening.
Our results raised two limits of the BiFC for a candidate interaction screening.
Some RING E3s ligases showed significant interaction signals when screened with Arabidopsis key regulatory proteins using AlphaScreen protein-protein interaction screening technology (unpublished data).
Among candidate regulatory factors is HaDREB2, which is expressed in immature embryos and was cloned by cis-element interaction screening.
In addition, the protein libraries described here can be used for further understanding E2-E3 specificities and as platforms for protein-protein interaction screening.
We predict the inductive herb-drug interactions through screening agonist of PXR.
This database contains genetic interactions extracted from both small-scale and high-throughput interaction screening studies.
To address these questions, we introduce here a computational approach for improving the quantitative discrimination power encoded in the genetic interaction screening data.
Genetic interaction screening in tractable model organisms constitutes a powerful alternative approach for candidate identification.
Genetic interaction screening is a powerful tool for the analysis of complex processes.
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