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To investigate how electrostatic interactions restrict the associations of coiled coils, we improved a heterodimeric coiled coil (WinZip-A1B1) by in vivo selection and, alternatively, by rational design.
Thus, subtle linkages among the inter-residue interactions restrict the possible combinations of amino acids that are able to form a well-folded structure in a family.
The model is set forward whereby these interactions restrict XPD processivity distinguishing it from more processive helicases in the family (such as FancJ and Rtel).
Compatible interactions allow bacterial growth within the host and disease development, whereas incompatible interactions restrict bacterial multiplication with minimal symptom development through the sacrifice of very few cells in the immediate vicinity of the pathogen by programmed cell death.
The ability of some plants to grow and reproduce in botanical gardens under other climatic conditions has also been interpreted to suggest that biotic interactions restrict their natural distributions (Vetaas, 2002), although the role of other factors in such studies often cannot be fully disentangled from the biotic interaction signal.
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The latter are deduced from pair interactions restricted to nearest neighbour atoms.
Autism spectrum disorders (ASD, or the "autisms") are a group of pervasive neurodevelopmental disorders that are characterized by delayed or abnormal development and use of language, poor reciprocal social interactions, restricted interests and repetitive behaviors [1].
However, the accommodation of both hydrophilic and hydrophobic interactions restricts molecular configurations, resulting in additional entropic effects (4).
In 1943, Kanner [ 5] described autism as a neurodevelopmental disorder with impairments in social interactions, restricted stereotyped interests, and abnormalities in verbal and nonverbal behavior.
The query defined finds the first 100 human interactions (restricted by maxResults) and the psicquicUrl provided corresponds to the IntAct database.
Once precise data on interaction specificity are available for a single representative site, a large number of interesting follow-up questions emerge: Are bilaterally specialized interactions restricted to more distinct microhabitat patches?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com