The gpDB Database is a relational database of GPCRs and GPCR interacting proteins based on interactions reported in the literature.
Size of the node indicates the number of positive interactions reported in the corresponding HTS assay.
To better understand the Condition × Vehicle interactions reported above, a between-subject ANOVA was performed on the z-transformed data from the IVIS-1 condition.
The network includes interactions between 198 genes reported by (Cooper et al. 2003) and 232 genes and their interactions reported in various peer reviewed publications (Additional file 2).
The integrated analysis of interactions reported from individual toxicology and pharmacology studies is of great importance giving systematic effects that may not be easily observed from the individual studies.
Using PathVisio, a pathway editor tool associated with WikiPathways, we created a gene interaction network of 430 rice (Oryza sativa) genes involved in the seed development process by curating interactions reported in the published literature.
Finally, four distinct target proteins representing members of three families, tRNA synthetases [50], phosphatases and kinases [51, 52] implicated in diseases such as cancer, were examined with 24 novel protein-ligand binding interactions reported.
Here we present an experiment, designed by the editorial board of FEBS Letters, aimed at integrating each manuscript with a structured summary precisely reporting, with database identifiers and predefined controlled vocabularies, the protein interactions reported in the manuscript.
For all interactions reported here, the attacker also won the interaction.
The first one contains all interactions reported in only one of the input data sets ('unique interactions') and the second one consists of interactions reported in more than one database ('common interactions').
Is a systems biology approach which would require to reveal all interactions including complex interactions reported here really feasible?
