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The domains involved in these interactions recognize specific peptide motifs in their binding partner, and this recognition can be further influenced by the presence of post-translational modifications, such as phosphorylation, ubiquitination or methylation.
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The LRR domain is likely to be involved in protein-protein interactions, recognizing pathogen elicitor molecules [ 14, 15].
Figure 1B presents a pattern of nine common interactions recognized by MAPPIS (six hydrogen bonds, two hydrophobic aliphatic and one aromatic).
The conserved interactions recognized by MAPPIS are formed by the known hot spots Tyr-434 and Asp-435 of Angiogenin with ΔΔ G of 3.3 and 3.5 kcal/mol respectively.
As most of the conserved interactions recognized by MAPPIS are created by regions with similar physico-chemical properties, the predictions made by MAPPIS are a subset of the predictions of MultiBind.
There is a strong consistency to the Facebook brand and interface interactions, people recognize Facebook and know how to use it without having to think too much.
The structure of ADMA-bound Tudor domains is a good example of how nature utilizes noncovalent cation−π interactions to recognize the arginine guanidinium group.
Our first task, when studying joint effects, is to understand the limitations of our definitions for "interaction," and recognize that what statisticians mean and what biologists might want to mean by interaction may not coincide.
Besides the absence of Hog1p-Ptp2p interaction, Ste20p-Ptp2p interaction was recognized.
More importantly, four pairs of interactions are recognized by the MARS model as: The interaction between CA (percentage of cultivated land area to total catchment area) and ASD shows that the cultivation can weaken the reducing effect of high ASD (>46.78 mm) on the Budyko parameter estimating.
Protein interaction modules, such as PDZ, SH3, WW, EH, SH2 and other domains, mediate protein-protein interactions by recognizing and binding short and usually linear peptide epitopes within their interacting partners [1] [4].
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