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The docking results suggest that L418A mutation influenced the binding interactions of the substrate with several residues in the active site of MtbICL.
Due to the distinct qualities of applied solvent and different interactions of the substrate with polymer brushes, matrix-dispersed surface morphologies with different dispersed phase regions were developed on poly ethylene glycol -b-polystyrene (PEglycol -b-polystyreneglycol -b-polystyrene(ethylene glycol)-b-PEG-b-PS /polyethylenete) (PEG-b-PS /polyethylenele-co-crystals.
Because SUMOylation can act by regulating the interactions of the substrate protein with other macromolecules, such information is useful.
However, it should be noted that an efficient synergistic hydrolysis was found in the interactions of the substrate with Xyl10Awt that has the highest xylan hydrolysis activity.
The ability to resolve different intermediate states and interactions of the substrate allows mechanistic questions to be addressed at a higher resolution.
Interactions of the substrate with the active site can be split into two categories: interactions with the carboxy and ammonium groups of L-tryptophan, and those with the indole ring system.
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These findings provide evidence that the amphitropic nature of LOXs is finely tuned by the interaction of the substrate with the residues of the active site, suggesting new strategies for the design of enzyme inhibitors.
Most of the research has progressed in the field of isolation, purification and characterization of Xylanases, without giving much emphasis on the interaction of the substrate and the enzyme.
Cyclic hexa- or tetranuclear copper II) species, exhibiting imidazolate-bridge groups between the copper centres, were observed to be better catalysts then the analogous dinuclear ones, mainly due the interaction of the substrate with the catalyst hydrophobic cavity.
The interaction of the substrate temperature and the deposition rate in a vacuum arc deposition process were investigated with regards to dependence on static and dynamic arc current parameters.
Results were explained by the steric hindrance of furfural by the surfactant molecules in micelles thus favoring the interaction of the substrate with hydroxyl groups in hydrous zirconia through the CO group.
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