Sentence examples for interactions of the native from inspiring English sources

Potential explanations are that single-domain immunogens may not possess the correct quaternary interactions of the native protein or reproduce the high affinity binding site(s).

The ease of measuring interactions of the native molecules without the use of labeled antigen-specific antibodies or other staining techniques, make label-free systems ideal for also investigating functional interactions between large multimeric glycoproteins and cellular receptors.

The results revealed that the dissociation constant (Kd) for the interaction of the native MUC1-CD peptides and Src-SH3 domain was weak with a Kd of 2 3 mM.

Thermodynamic considerations dictate that the stability of a particular protein in dilute solution is directly linked to the difference between the respective free energies of nonspecific interaction of the native and non-native conformations of the selected protein and the macromolecular constituents of the surrounding medium [10], [11].

Selected blockers were also able to inhibit the interaction of the native complex of AnxA2 and S100A10 and some were shown to inhibit the complex inside the cell.

When P4 and P6 were fused with a phosphodiester linkage, the resulting RNA retained the detailed tertiary interactions characteristic of the native P4-P6 domand and even required lower magnesium ion concentrations for folding.

We therefore also marked these as possible contaminants in our interaction lists, as they are less likely to represent bona fide interactions of the untagged native proteins.

Analysis of the mutation-induced perturbation of the non-covalent interaction RIN of the native PapC TD in the absence of the β-hairpin, α-helix, or both, shows that the interactions between nodes that are not part of the deleted secondary structure elements are consistently weakened.

The present work deals with investigating the role of ionic interactions in the native conformation of BmGK by altering pH and salt concentration as well as by disruption of inter-subunit region.

Extending this to other diseases will need to be supported by detailed genomic analyses of the human microbiota, together with a better understanding of the interactions between the native or medically altered microbiome and host immunity.

The main advantage of the above-mentioned approaches consists of the possibility of detecting receptor receptor interactions in the native context.