Sentence examples for interactions of novel from inspiring English sources

Docking evaluations provided insight into enzyme inhibitory interactions of novel synthesized compounds with the BACE1 active site involving a critical role for Gln73 and/or Phe108 alongside of Asp32.

Hybrids can outperform parental species in certain environments through the interactions of novel allelic arrangements (Birchler et al. 2006) or have less genetic variation than parental populations (Norris et al. 1999).

A novel type of supramolecular aggregate, named a "nanosponge" was synthesized through the interaction of novel supramolecular building blocks with trigonal geometry.

Interaction of novel experimental drug therapies with conventional treatment and management practices may have clouded the interpretations of results of phase 3 efficacy trials.

The structural basis for the interaction of novel inhibitors with tubulin was investigated by molecular modeling, and we have proposed binding models for these hit compounds with tubulin.

This work provides a new vista on the integration and interaction of novel low-dimensional nanofillers with bulk 3D metal matrices.

In our effort to further understand interaction of novel pyran derivatives with monoamine transporters, we have designed, synthesized, and biologically characterized side-chain-extended derivatives of our earlier developed cis- and trans- 6-benzhydryl-tetrahydro-pyran-3-yl -benzylamine derivatrans- 6-benzhydryl-tetrahydro-pyran-3-yl -benzylamine

This is the first study evaluating the pharmacological interaction of novel LDH inhibitors with gemcitabine in pancreatic cancer.

This can arise in hybrids via increased heterozygosity, which could mask deleterious alleles (dominance model) or through the interaction of novel allele combinations, which produce a superior phenotype (overdominance model) (Birchler et al. 2006).

The muscle-isoform of lactate dehydrogenase (LDH-A) constitutes a major checkpoint for the switch to anaerobic glycolysis, ensuring supply of energy and anabolites in hypoxic-environments. Therefore, we investigated the molecular mechanisms underlying the pharmacological interaction of novel LDH-A inhibitors in combination with gemcitabine in PDAC cells.

Interactions scores of novel anti-HER2 antibodies ranged between 1.40 and 3.08, all indicative of an antagonistic interaction with TNF-α.