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Since the candidate interspecies network cannot accurately represent actual C. albicans-zebrafish interactions, it should be further validated and pruned.
Among genes that may be involved in plant-bacteria interactions, it should be noted that the D. dadantii iaaMH genes (Dda3937_01279 and 01280) allowing the production of an auxin plant hormone, do not have counterparts in D. solani.
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If one of the complex subunits has a feature, for instance, a PTM, that is important to describe the interaction, it should be possible to discriminate between the different subunits of the complex and specify on which subunit the feature is located.
If there is no such interaction then it should be possible to add the relative risks posed by the vectors in arriving at the overall relative risk posed to a given cell.
3 The first test of our interaction with IT should be whether it leads to better, and quicker, decisions.
The strong contribution of multiple cation−π interactions might also provide a plausible mechanism to exclude an uncharged peptidyl citrulline from binding to Tudor domains as it cannot form this type of interaction, although it should be noted that this has not been systematically tested.
Ideally, as cooperativity is intrinsic to molecular interactions in biology, it should be inherent to a molecular interaction standard.
Since this model takes into account the pair-wise interactions between SNPs, it should be at least as accurate as the GCI score, which does not consider them.
In the interaction presented above, it should be noted that the elements in bold are not associated with an explicit Subject.
If this interaction is robust, it should be straightforward to demonstrate this for Irgb2-b1.
Although the original identification of the Gab2/GC-GAP interaction in the Y2H screen suggests a direct interaction between both proteins, it should be noted that GC-GAP also interacts in mammalian cells with the N-terminal SH3 domain of Crk [ 78].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com