This paper investigates the effects of social interaction information from friends on commuters' daily route choice decisions.
By incorporating the interaction information from signaling pathways, we revealed associations between genomic alterations and drug responses that could be missed when using a gene-centric approach.
Automatic extracting protein protein interaction information from biomedical literature can help to build protein relation network, predict protein function and design new drugs.
Further, VisANT retrieves the interaction information from databases such as BIND, MIPS, Biogrid, HPRD and CAGT.
One reason is that the available databases, such as HPRD, contain protein-protein interaction information from a variety of cell types and under a variety of conditions.
For the PKC kinase family, which also has about ten percent increase in accuracy, the protein-protein interaction information from the STRING database are the most powerful.
We used eight functional feature types defined by UniProt annotations − ACT_SITE, BINDING, CA_BIND, DISULFID, DNA_BIND, LIPID, METAL, and NP_BIND (see Material and Methods for details) − and protein-protein interaction information from PICCOLO database (GR. Bickerton, unpublished).
We also downloaded protein interaction information from HPRD.
There are also methods that combine interaction information from several different data sources [ 27].
The gene interaction information from DRYGIN was converted to a symmetric Boolean matrix.
