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It is thus an excellent model system to explore genetic and cellular interactions in development and homoeostasis.
Rodent incisors provide a classic model for studying epithelial mesenchymal interactions in development.
This work shows that multiple factors influence the dynamics of chromatin interactions in development.
This removal of ligands is of critical importance in signaling in epithelial-mesenchymal interactions in development.
Adhesion-GPCRs provide essential cell-cell and cell-matrix interactions in development, and have been implicated in inherited human diseases like Usher Syndrome and bilateral frontoparietal polymicrogyria.
Here, we focus on one molecular program that may play a role in mesenchymal-epithelial interactions in development and cancer– the transcriptional response of fibroblasts to Wnt signals.
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Institution: Global Public Policy Institute, Interaction in Development "With the aim to continuously improve transparency and use of evaluation, UNICEF Evaluation Office manages the "Global Evaluation Reports Oversight System".
The organization of the AL neuropil in MβCD-treated animals was disrupted in several ways that suggest that gMSD-based signaling affects several of the cellular interactions involved in development of the antennal lobe.
The use of in vitro and in vivo extrapolation methods in early drug discovery has expanded in an effort to provide information on drug clearance and potential drug drug interactions earlier in development.
Though experimental animal studies have revealed that statins can inhibit or even diminish the development of atherosclerosis [ 15, 16], their effect on leukocyte-endothelial interactions in the development of atherosclerosis has not been demonstrated in vivo.
Here we investigate the role of 10 potential SNPs in XRCC3, BRCA2, RAG1, XRCC5, LIG4, XRCC4 and ATM in the development of gliomas, and further evaluate their gene-gene and gene-environment interactions in the development of glioma.
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