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Their method emphasized the enrichment of synthetic lethal interactions connecting two pathways.
A node in a network is randomly selected, and the selected node is eliminated from the network with a probability δ together with all interactions connecting to the selected node.
The graph contained 156,459 interactions connecting 15,494 genes.
We propose that a functional module demonstrates high strength if it has more internal interactions connecting the molecules inside it than the external interactions connecting it to the rest of the network.
Figure 7a shows a network of protein interactions connecting Dp10 trisomic genes with estrogen, progesterone, androgen, and thyroid hormone receptors.
Every group forms a compact network with physical protein interactions connecting most group members in one or two steps.
Similar(27)
Thus from the hydrogen bond connectivity array (see Fig. 3) it can be seen that six interactions connect A and B molecules (excluding interactions between molecules A and B) while there are three AA and three BB types.
In the compound II, C-H…O interactions connect the molecules to form an R22 (16) dimer running along 011 direction.
Globally, chromosomes are organized into active and inactive compartments while, at the gene level, looping interactions connect promoters to regulatory elements.
Many network interactions connect the few transcripts altered on day 1 and the many altered on later days.
This complex network of interactions connects the two α-helix domains of p6 [40] and may be of structural or functional significance.
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